@inproceedings{13135, author = {Peter Kekenes-Huskey and Andrew Edwards and Johan Hake and Anushka Michailova and Andrew McCammon and Andrew McCulloch}, title = {A Markov-State Model for the Regulation of the Sarcoplasmic Reticulum Ca2+ ATPase by Phospholamban}, abstract = {Compelling evidence suggests that reduced sarcoplasmic reticulum (SR) Ca 2+ uptake via the SR Ca 2+ ATPase (SERCA) is a major contributor to the development of Ca 2+ signaling abnormalities in heart failure, and equally important as other known contributors to impaired Ca 2+ handling.}, year = {2014}, journal = {Annual meeting in Biophysical society}, volume = {106}, month = {01/2014}, publisher = {Elsevier}, }